Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline Copa Airlines

The cheapest airline(s) flying from Panama City to Medellin is Copa Airlines.

  • Copa Airlines Copa Airlines
  • Avianca Avianca
  • United Airlines United Airlines
Cheapest Month September

Travel Period: February 2025 - January 2026

The cheapest month(s) to fly from Panama City to Medellin is September.

  • Feb 2025
  • Mar 2025
  • Apr 2025
  • May 2025
  • Jun 2025
  • Jul 2025
  • Aug 2025
  • Sep 2025
  • Oct 2025
  • Nov 2025
  • Dec 2025
  • Jan 2026
Cheapest Day of the Week Friday

The cheapest day(s) of the week to fly from Panama City to Medellin is Friday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday

Flight Schedules

Last Updated: Thu, 2 Jan, 2025

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  • Availability
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  • 11:20 PTY
    12:30 MDE
    1Hrs, 10m Direct
  • PTYPanama City Tocumen International Airport 11:20 - MDE 12:30 1h 10m Direct
  • PTYPanama City Tocumen International Airport 11:20
  • MDEMedellin Jose Maria Cordova Intl Airport 12:30
  • 1h 10m
  • Direct
  • Avianca (AV 323)Airbus
  • Avianca (AV 323)
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    • S
  • Airbus
  • 15:34 PTY
    16:44 MDE
    1Hrs, 10m Direct
  • PTYPanama City Tocumen International Airport 15:34 - MDE 16:44 1h 10m Direct
  • PTYPanama City Tocumen International Airport 15:34
  • MDEMedellin Jose Maria Cordova Intl Airport 16:44
  • 1h 10m
  • Direct
  • Avianca (AV 317)Airbus
  • Avianca (AV 317)
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    • S
    • S
  • Airbus
  • 11:25 PTY
    15:48 MDE
    4Hrs, 23m 1 Stop (BOG)
  • PTYPanama City Tocumen International Airport 11:25 - MDE 15:48 4h 23m 1 Stop (BOG) Bogota
  • PTYPanama City Tocumen International Airport 11:25
    BOGBogota Airport 14:47
  • BOGBogota Airport 13:00
    MDEMedellin Jose Maria Cordova Intl Airport 15:48
  • 4h 23m (1h 47m)
  • 1 Stop BOG · Bogota 1h 47m
  • Avianca (AV 8383)Airbus
    Avianca (AV 9306)Airbus
  • Avianca (AV 8383)
    • M
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  • 11:25 PTY
    15:48 MDE
    4Hrs, 23m 1 Stop (BOG)
  • PTYPanama City Tocumen International Airport 11:25 - MDE 15:48 4h 23m 1 Stop (BOG) Bogota
  • PTYPanama City Tocumen International Airport 11:25
    BOGBogota Airport 14:47
  • BOGBogota Airport 13:00
    MDEMedellin Jose Maria Cordova Intl Airport 15:48
  • 4h 23m (1h 47m)
  • 1 Stop BOG · Bogota 1h 47m
  • Avianca (AV 59)Airbus A320 Neo
    Avianca (AV 9306)Airbus
  • Avianca (AV 59)
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  • 13:30 PTY
    18:09 MDE
    4Hrs, 39m 1 Stop (SJO)
  • PTYPanama City Tocumen International Airport 13:30 - MDE 18:09 4h 39m 1 Stop (SJO) San Jose
  • PTYPanama City Tocumen International Airport 13:30
    SJOSan Jose Juan Santamaria Airport 15:14
  • SJOSan Jose Juan Santamaria Airport 13:45
    MDEMedellin Jose Maria Cordova Intl Airport 18:09
  • 4h 39m (1h 29m)
  • 1 Stop SJO · San Jose 1h 29m
  • Avianca (AV 642)Airbus A320 Neo
    Avianca (AV 25)Airbus
  • Avianca (AV 642)
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  • 17:25 PTY
    21:55 MDE
    4Hrs, 30m 1 Stop (BOG)
  • PTYPanama City Tocumen International Airport 17:25 - MDE 21:55 4h 30m 1 Stop (BOG) Bogota
  • PTYPanama City Tocumen International Airport 17:25
    BOGBogota Airport 20:59
  • BOGBogota Airport 18:55
    MDEMedellin Jose Maria Cordova Intl Airport 21:55
  • 4h 30m (2h 04m)
  • 1 Stop BOG · Bogota 2h 04m
  • Avianca (AV 61)Airbus
    Avianca (AV 9250)Airbus
  • Avianca (AV 61)
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  • 18:30 PTY
    22:49 MDE
    4Hrs, 19m 1 Stop (BOG)
  • PTYPanama City Tocumen International Airport 18:30 - MDE 22:49 4h 19m 1 Stop (BOG) Bogota
  • PTYPanama City Tocumen International Airport 18:30
    BOGBogota Airport 21:44
  • BOGBogota Airport 20:00
    MDEMedellin Jose Maria Cordova Intl Airport 22:49
  • 4h 19m (1h 44m)
  • 1 Stop BOG · Bogota 1h 44m
  • Avianca (AV 89)Airbus
    Avianca (AV 8458)Airbus
  • Avianca (AV 89)
    • M
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What’s the fastest flight time from Panama City to Medellin?

The fastest flight time for direct flights from Panama City to Medellin is 1 hour 10 minutes. Check latest flight schedules & prices on Wego.

What’s the most popular airline flying from Panama City to Medellin?

The most popular airline flying from Panama City to Medellin is Avianca. Find the latest flight deals on Wego.

How far is Medellin from Panama City?

The flight distance between Panama City and Medellin is 530km. Check all available flights on Wego.

When is the earliest and latest flight of the day?

The earliest flight of the day departs at 11:20. The last flight of the day departs at 11:20. See the full list of flight times on Wego.

How many airlines offer direct flights from Panama City to Medellin?

There are 1 airlines that offer direct flights from Panama City to Medellin. Find out the list of airlines on Wego.